预防兽医学系

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  • 宫鹏涛教授
  • 性别:男
  • 职称:教授
  • 硕导/博导:博导
  • 学科专业:预防兽医学
  • 最高学位:博士
  • 研究方向:动物及人兽共患寄生虫病学
  • 最高学历:研究生
  • 邮箱:gongpt@jlu.edu.cn

讲授课程

本科生:动物寄生虫病学;动物寄生虫病学实习;人兽共患病学;动物医学各论

硕士生:预防兽医学实践,现代寄生虫学;

博士生:现代寄生虫学;

 

教育经历

1999/09-2004/06解放军军需大学,学士

2004/09-2007/06最全菠菜导航网,51菠菜网,预防兽医学,硕士

2009/09-2016/12最全菠菜导航网,51菠菜网,预防兽医学,博士

 

工作经历

1999/09-2004/06解放军军需大学,学员旅,学员

2004/07-2004/08解放军军需大学,学员旅,助理员

2004/09-2008/09 最全菠菜导航网,畜牧兽医学院,助教

2008/10-2013/09 最全菠菜导航网,51菠菜网,讲师

2013/10-2019/12 最全菠菜导航网,51菠菜网,副教授,教研室主任

2017.10 最全菠菜导航网,51菠菜网,破格获得教授资格

2018/01-至今最全菠菜导航网,51菠菜网,博士生导师

2019/10-2020/08 美国南加州大学,凯克医学院,访问学者

2020/01-至今最全菠菜导航网,51菠菜网,教授,教研室主任

 

科研项目

1.长春市科技计划项目,基于CRISPR-Cas12系统的牛贾第虫和隐孢子虫快速检测方法的建立与应用(21ZY24),202201-202312,30.00万元,在研;

2.吉林省科技发展计划技术攻关项目,鸡球虫四价重组亚单位疫苗的研制(20190301089NY),2019.01-2021.12,50.00万元,在研;

3.国家自然科学基金面上项目,贾第虫病毒影响贾第虫致病性的分子识别机制(31772732),201801-202112,61.00万元,结题;

4.最全菠菜导航网优秀青年教师培育计划,2018.01-2010.12,40.00万元,结题;

5.最全菠菜导航网学科交叉项目,贾第虫病毒相关TLRs信号通路对贾第虫致病性的影响,2019,20.00万元,结题;

6.973项目子课题,新孢子虫带虫空泡形成关键蛋白分子的鉴定与功能(2015CB150305-2),201501-201912,97.68万元,结题;

7.国家科技支撑计划子课题,实验用动物寄生虫快速检测新技术研究(2015BAI07B02-10),201504-201712,60.00万元,结题;

8.国家自然科学基金青年基金,贾第虫病毒非编码RNA克隆及功能分析(31101804),201201-201412,23.00万元,结题;

9.广州市科技计划,重要水源性人兽共患寄生虫病分子流行病学调查及人兽互传风险评估(2013J4100124),201301-201412,3.20万元,结题;

10.广东省科技计划,广东省隐孢子虫分子流行病学调查及人兽互传风险评估(20110323),201101-201312,4.00万元,结题;

11.吉林省科技发展计划,隐孢子虫胶体金免疫层析检测试纸的研制(20100160),2010-2012,5.00万元,结题。

 

学术论文

1.Gao Y#, Li X#, Zhang N#, Zhao P, Li S, Tai L, Li X, Li L, Li J, Zhang X, Sun M, Cao L*,Gong P*.Trichomonas vaginalisinduces extracellular trap release in mouse neutrophils in vitro. Acta Biochim Biophys Sin (Shanghai). 2021 Dec 8;53(12):1736-1738. doi: 10.1093/abbs/gmab139.

2.Wei R, Li X, Wang X, Zhang N, Wang Y, Zhang X,Gong P*, Li J*.Trypanosoma evansievades host innate immunity by releasing extracellular vesicles to activate TLR2-AKT signaling pathway. Virulence. 2021 Dec;12(1):2017-2036. doi: 10.1080/21505594.2021.1959495.

3.Yue TT#, Zhang N#, Li JH, Lu XY, Wang XC, Li X, Zhang HB, Cheng SQ, Wang BB,Gong PT*, Zhang XC*.Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma andTrichinella spiralis. Parasit Vectors. 2021 Sep 26;14(1):498. doi: 10.1186/s13071-021-05008-6.

4.Cao L, Zhao P, Ding HE, Wang N, Zhang X, Yuan S, Dong H, Guo Y, Yao X, Yu Q, Shao H,Gong P*. Development of a double antibodies sandwich ELISA for the detection of avian leukosis virus subgroup J based on monoclonal antibodies against gp85. Acta Biochim Biophys Sin (Shanghai). 2021 Oct 12;53(10):1408-1411. doi: 10.1093/abbs/gmab114.

5.Pu X#, Li X#, Cao L#, Yue K, Zhao P, Wang X, Li J, Zhang X, Zhang N, Zhao Z, Liang M,Gong P*. Giardia duodenalisInduces Proinflammatory Cytokine Production in Mouse Macrophages via TLR9-Mediated p38 and ERK Signaling Pathways. Front Cell Dev Biol. 2021 Jul 15;9:694675. doi: 10.3389/fcell.2021.694675. eCollection 2021.

6.Zhao P#, Cao L#, Wang X#, Li J, Dong J, Zhang N, Li X, Li S, Sun M, Zhang X, Liang M, Pu X,Gong P*.Giardia duodenalisextracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways. Parasit Vectors. 2021 Jul 8;14(1):358. doi: 10.1186/s13071-021-04865-5.

7.Wei R, Li X, Wang X, Wang Y, Zhang X, Zhang N, Wang J, Yang J, Zhang X,Gong P*, Li J*.Trypanosoma evansi triggered neutrophil extracellular traps formation dependent on myeloperoxidase, neutrophil elastase, and extracellular signal-regulated kinase 1/2 signaling pathways.Vet Parasitol. 2021 Aug;296:109502. doi: 10.1016/j.vetpar.2021.109502.

8.Zhao P#, Dong J#, Cao L#, Li J, Zhang X, Li X, Wang X, Bello BK, Zhang N*,Gong P*.A Newly Discovered Dense Granule Protein 3 inNeospora caninum.Acta Parasitol. 2021 Dec;66(4):1581-1585. doi: 10.1007/s11686-021-00402-7.

9.Li S#, Zhang N#, Liu S, Li J, Liu L, Wang X, Li X, Gong P*, Zhang X*.Protective Immunity AgainstNeospora caninumInfection Induced by 14-3-3 Protein in Mice. Front Vet Sci. 2021 Mar 3;8:638173. doi: 10.3389/fvets.2021.638173.

10.Dong J#, Zhang N#, Zhao P#, Li J, Cao L, Wang X, Li X, Yang J, Zhang X*,Gong P*.Disruption of Dense Granular Protein 2 (GRA2) Decreases the Virulence ofNeospora caninum.Front Vet Sci. 2021 Feb19;8:634612. doi:10.3389/fvets.2021.634612.

11.Zhao P#, Cao L#, Wang X#, Dong J, Zhang N, Li X, Li J, Zhang X,Gong P*. Extracellular vesicles secreted byGiardia duodenalisregulate host cell innate immunity via TLR2 and NLRP3 inflammasome signaling pathways. PLoS Negl Trop Dis. 2021 Apr 2;15(4):e0009304. doi: 10.1371/journal.pntd.0009304.

12.Gong P, Li X, Wu W, Cao L, Zhao P, Li X, Ren B, Li J*, Zhang X*. A Novel MicroRNA From the Translated Region of the Giardiavirus rdrp Gene Governs Virus Copy Number inGiardia duodenalis.Front Microbiol. 2020 Nov 23;11:569412. doi: 10.3389/fmicb.2020.569412.

13.Zhao P#, Zhang N#, Dong J#, Li J, Wang X, Li X, Li X, Yang J,Gong P*, Zhang X*.Effects of Dense Granular Protein 6 (GRA6) Disruption onNeospora caninumVirulence.Front Vet Sci. 2020 Sep 22;7:562730. doi: 10.3389/fvets.2020.562730.

14.Li L#, Wang XC#,Gong PT#, Zhang N, Zhang X, Li S, Li X, Liu SX, Zhang XX, Li W, Li JH*, Zhang XC*.ROS-mediated NLRP3 inflammasome activation participates in the response against Neospora caninum infection. Parasit Vectors. 2020 Sep 5;13(1):449. doi: 10.1186/s13071-020-04331-8.

15.Wang X#, Li X#,Gong P#, Zhang N, Li L, Ouyang H, Jia L, Li J*, Zhang X*.Pyroptosis executioner gasdermin D contributes to host defense and promotes Th 1 immune response during Neospora caninum infection.Vet Parasitol. 2020 Oct;286:109254. doi: 10.1016/j.vetpar.2020.109254.

16.Li X#, Zhang N#, Wu N, Li J, Yang J, Yu Y, Zheng J, Li X, Wang X,Gong P*, Zhang X*. Identification of GdRFC1 as a novel regulator of telomerase inGiardia duodenalis. Parasitol Res. 2020 Mar;119(3):1035-1041. doi: 10.1007/s00436-020-06610-w.

17.Cao L#, Jiang W#, Cao S#, Zhao P, Liu J, Dong H, Guo Y, Liu

Q*,Gong P*. In vitro leishmanicidal activity of antimicrobial peptide KDEL against Leishmania tarentolae. Acta Biochim Biophys Sin (Shanghai). 2019 Dec 13;51(12):1286-1292.doi: 10.1093/abbs/gmz128.

18.Chang L#, Zhang X#,Gong P#,Wang Y, Du B, Li J*. Identification and characterization of Letm1 gene inToxoplasma gondii.Acta Biochim Biophys Sin (Shanghai). 2019 Jan 1;51(1):78-87. doi: 10.1093/abbs/gmy138.

19.Xin C#, Li J#,Gong P#, Wu B, Zhang N, Yang J, Cai X*, Zhang X*.Viral RNA-based transfection and expression of enhanced green fluorescent protein in the parasitic protozoanEimeria stiedae.Acta Biochim Biophys Sin (Shanghai). 2019 Feb 1;51(2):216-218. doi: 10.1093/abbs/gmy155.

20.Wang X#,Gong P#,Zhang N, Li L, Chen S, Jia L, Liu X, Li J*, Zhang X*.Inflammasome activation restrains the intracellularNeospora caninum proliferation in bovine macrophages.Vet Parasitol. 2019 Apr;268:16-20.

21.Li S#,Gong P#, Zhang N, Li X, Tai L, Wang X, Yang Z, Yang J, Zhu X, Zhang X*, Li J*.14-3-3 Protein of Neospora caninum Modulates Host Cell Innate Immunity Through the Activation of MAPK and NF-κB Pathways.Front Microbiol. 2019 Jan 25;10:37. doi: 10.3389/fmicb.2019.00037. eCollection 2019.

22.Tai L#, Li J#, Yin J, Zhang N, Yang J, Li H, Yang Z,Gong P*, Zhang X*,. A novel detection method ofCryptosporidium parvuminfection in cattle based onCryptosporidium parvumvirus 1Acta Biochim Biophys Sin (Shanghai). 2019 Jan 1;51(1):104-111.

23.Fei L#, Zhengkai W#, Weina J#, Lili C, Yuhang G, Zhengtao Y, Jianhua L, Biao Y, Xichen Z*,Pengtao G*,.Trichomonas vaginalis triggers the release of THP-1 extracellular traps. Parasitol Res. 2019 Jan;118(1):267-274.

24.Wang P#,Gong P#, Wang W, Li J, Ai Y, Zhang X.An Eimeria acervulina OTU protease exhibits linkage-specific deubiquitinase activity. Parasitol Res. 2019 Jan;118(1):47-55.

25.Wang X#,Gong P#, Zhang X, Li S, Lu X, Zhao C, Yu Q, Wei Z, Yang Y, Liu Q, Yang Z, Li J*, Zhang X*. NLRP3 Inflammasome Participates in Host Response to Neospora caninumInfection. Front Immunol. 2018 Jul 30;9:1791.

26.Li S#,Gong P#, Tai L, Li X, Wang X, Zhao C, Zhang X, Yang Z, Yang J, Li J*, Zhang X*. Extracellular Vesicles Secreted byNeospora caninumAre Recognized by Toll-Like Receptor 2 and Modulate Host Cell Innate Immunity Through the MAPK Signaling Pathway. Front Immunol. 2018 Jul 24;9:1633.

27.Wang W#,Gong P#, Wang P, Dong J, Wang X, Yang Z, Li J*, Zhang X*. A novel dense granule protein NcGRA23 inNeospora caninum. Acta Biochim Biophys Sin (Shanghai). 2018 Jul 1;50(7):727-729.

28.Wang X#, Li J#,Gong P#, Li X, Zhang L, He B, Xu L, Yang Z, Liu Q*, Zhang X*.Detection of Neospora caninum DNA by polymerase chain reaction in bats from Southern China. Parasitol Int. 2018 Mar 23;67(4):389-391.

29.Dong J#, Li J#, Wang X, Yang J,Gong P*, Zhang X*.A karyozoic phenomenon forNeospora caninum.Acta Biochim Biophys Sin (Shanghai).2018 Mar 1;50(3):313-315.

30.Hou H#, Cao L#, Ren W#, Wang D, Ding H, You J, Yao X, Dong H, Guo Y, Yuan S, Zhang X,Gong P*.Seroprevalence of Dirofilaria immitis in Cats from Liaoning Province, Northeastern China.Korean J Parasitol. 2017 Dec;55(6):673-677.

31.Li X#, Li J#, Zhang X, Yang Z, Yang J,Gong P*.Prevalence ofPentatrichomonas hominisinfections in six farmed wildlife species in Jilin, China.Vet Parasitol. 2017 Sep 15;244:160-163.

32.Wang P, Wang W, Yang J, Ai Y,Gong P* Zhang X*.A novel telomerase-interacting OTU protein ofEimeria tenellaand its telomerase-regulating activity. Acta Biochim Biophys Sin (Shanghai).2017 Aug 1;49(8):744-745.

33.He X#,Gong P#, Wei Z, Liu W, Wang W, Li J, Yang Z*,Zhang X*.Peroxisome proliferator-activated receptor-γ-mediated polarization of macrophages inNeospora caninuminfection.Exp Parasitol. 2017 Jul;178:37-44.

34.Wang X#,Gong P#, Zhang X, Wang J, Tai L, Wang X, Wei Z, Yang Y, Yang Z, Li J*, Zhang X*.NLRP3 inflammasome activation in murine macrophages caused byNeospora caninuminfection.Parasit Vectors. 2017 May 30;10(1):266.

35.He D#,Pengtao G#, Ju Y, Jianhua L*, He L, Guocai Z, Xichen Z*. Differential Protein Expressions in Virus-Infected and UninfectedTrichomonas vaginalis.Korean J Parasitol.2017 Apr;55(2):121-128.

36.Dong J#, Li J#, Wang J, Li F, Yang J,Gong P*, Li H, Zhang X*.Identification and characterization of GRA6/GRA7 ofNeospora caninumin MDBK cells.Acta Biochim Biophys Sin. 2017 Apr 1;49(4):361-366.

37.Li M#, Zhang X#,Gong P#, Li J*.Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage.Parasit Vectors. 2016 Aug 8;9(1):438.

38.Gong P#, Cao L#, Guo Y, Dong H, Yuan S, Yao X*, Ren W, Yao L, Xu Z, Sun Q, Zhang X*.Toxoplasma gondii: Protective immunity induced by a DNA vaccine expressing GRA1 and MIC3 against toxoplasmosis in BALB/c mice. Exp Parasitol. 2016 Jul;166:131-6.

39.Li W#, Li W#,Gong P#, Zhang C, Yang J, Zhang X*, Li J*.The prevalence of intestinal trichomonads in Chinese pigs. Vet Parasitol.2015 Jun30; 211 (1-2) :12-5

40.Zhao N#,Gong P#, Cheng B, Li J*, Yang Z, Li H, Yang J, Zhang G, Zhang X*.Eimeria tenella: 14-3-3 protein interacts with telomerase.Parasitol Res 2014 Oct;113 (10) :3885-9.

41.Zhao N#,Gong P#, Li Z, Cheng B, Li J*, Yang Z, Li H, Yang J, Zhang G, Zhang X*.Identification of a telomeric DNA-binding protein inEimeria tenella.Biochem Biophys Res Commun. 2014 Sep 5;451(4):599-602.

42.Li W#, Li W#,Gong P#, Meng Y, Li W, Zhang C, Li S, Yang J, Li H, Zhang X*, Li J*.Molecular and morphologic identification ofPentatrichomonas hominisin swine. Vet Parasitol. 2014 May 28;202(3-4):241-7.

43.Wu W#,Gong P#, Li J*, Yang J, Zhang G, Li H, Yang Z, Zhang X*.Simple and nonradioactive detection of microRNAs using digoxigenin (DIG)-labeled probes with high sensitivity.RNA. 2014 Apr;20(4):580-4.

44.Yu Q#, Huang X#,Gong P*, Zhang Q, Li J, Zhang G, Yang J, Li H, Wang N, Zhang X*.Protective immunity induced by a recombinant BCG vaccine encoding the cyclophilin gene ofToxoplasma gondii. Vaccine. 2013 Dec 9;31(51):6065-71.

45.Gong P#, Huang X#, Yu Q, Li Y, Huang J, Li J*, Yang J, Li H, Zhang G, Ren W, Zhang X*.The protective effect of a DNA vaccine encoding theToxoplasma gondii cyclophilin gene in BALB/c mice. Parasite Immunology, 2013,Mar-Apr;35, 140–146.

46.Deng B#,Gong P#, Li J*, Cheng B, Ren W, Yang J, Li H, Zhang G, Zhang X*.Identification of the differentially expressed genes in SP2/0 myeloma cells from Balb/c mice infected withTrichinella spiralis. Vet Parasitol. 2013 May 20;194(2-4):179-82.

47.Gong P, Zhang J, Cao L, Nan Z, Li J*, Yang J, Fang H, Jiao H, Jiang T, Su L, Zhang X*.Identification and characterization of myeloma-associated antigens inTrichinella spiralis.Exp Parasitol. 2011 Apr;127(4):784-8.

 

著作教材

1.《动物寄生虫病学》(第四版),科学出版社,副主编,2017;

2.《医学寄生虫图鉴》,人民卫生出版社,参编,2012;

3.《动物寄生虫病学》(第三版),科学出版社,副主编,2010;

4.《动物寄生虫病学实验指导》,最全菠菜导航网出版社,主编,2009;

5.《兽医公共卫生学》,中国轻工业出版社,参编,2009;

 

获奖情况

1.宫鹏涛(3/8),4种原虫病毒的分离鉴定、全基因组破译及转染原虫载体的构建,吉林省自然科学二等奖,2019。

2.宫鹏涛(4/13),人兽共患隐孢子虫病诊断与防治技术(2013J20021),吉林省科技进步二等奖,2013。

3.宫鹏涛(5/15),鸡球虫宿主细胞侵入分子及其保护性免疫机制研究(2011J10026),吉林省科学技术进步奖一等奖,2011;

4.宫鹏涛(3/12),我国贾第虫病毒的分离鉴定及其转染载体构建与应用(2009J20038),吉林省科学技术进步奖二等奖,2009;

5.宫鹏涛(3/5),《动物寄生虫病学》,首批国家一流本科课程,2019.10,教育部;

6.宫鹏涛,最全菠菜导航网2018-2019学年本科课堂教学质量“卓越奖”,2019.09;

7.宫鹏涛,最全菠菜导航网首届智慧课堂教学创新大赛暨长春市2019年职工技能大赛二等奖,2019.08;

8.宫鹏涛(5/11),《动物寄生虫病学》,国家精品资源共享课程,2016.10,教育部;

 

社会兼职

1.中国动物学会寄生虫专业委员会青年委员,2017.01-2020.12

2.中国畜牧业协会鹿业分会鹿疫病预防专家委员会委员,2019.04-

3.吉林省寄生虫学会秘书长,2020.01-

4.吉林省人兽共患病学会理事,2014.06-

5.Cells、Front Cell Infect Microbiol、Front Microbiol.、Parasite & Vectors、延边大学农学学报等杂志审稿人。

 

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