青年学者

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  • 雷林副教授
  • 性别:男
  • 职称:副教授
  • 硕导/博导:博导
  • 学科专业:临床兽医学
  • 最高学位:博士
  • 研究方向:动物营养代谢病
  • 最高学历:研究生
  • 邮箱:leilin@jlu.edu.cn

讲授课程

本科生:兽医临床诊断学

教育经历

(1)2016-10 至 2020-10,法国索邦大学(Sorbonne University),病理学与病理生理学, 博士

(2)2013-09 至 2016-06,最全菠菜导航网,临床兽医学,硕士

(3)2009-09 至 2013-06,河南科技大学,动物医学,学士

工作经历

(1)2023-12至今,最全菠菜导航网,51菠菜网,唐敖庆青年学者/人才引进副教授,博士生导师

(2)2021-04至2023-12,最全菠菜导航网,51菠菜网,博士后国(境)外交流计划引进博士后

科研项目

(1)2024-01至2026-12,基于单细胞核转录组测序揭示围产期奶牛脂肪过度动员组织微环境及其关键驱动因子,国家自然科学基金委员会,青年科学基金,30万

(2)2022-08 至 2023-12,IL11-JNK信号通路在酮病奶牛肝脏胰岛素抵抗中的调控机制,中国博士后科学基金会,面上项目,8万

(3)CD36在脂肪肝奶牛肝脏脂毒性中的作用机制(吉林省教育厅),2.5万

学术论文

1.Lin Lei,Alix Bruneau, Haquima El Mourabit, Justine Guégan, Trine Folseraas, Sara Lemoinne, Tom Hemming Karlsen, Bénédicte Hoareau, Romain Morichon, Ester Gonzalez-Sanchez, Claire Goumard, Vlad Ratziu, Pierre Charbord, Jérémie Gautheron, Frank Tacke, Thierry Jaffredo, Axelle Cadoret*, Chantal Housset*Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis,HEPATOLOGY, 2022, 76(5): 1360-1375.

2.Yiwei Zhu#,Lin Lei#, Xinghui Wang, Linfang Chen, Wei Li, Jinxia Li, Chenchen Zhao, Xiliang Du, Yuxiang Song, Wenwen Gao, Guowen Liu*, Xinwei Li*The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation.Acta Pharmaceutica Sinica B. 2023, 13(4): 1616-1630.

3.Zhiyuan Fang, Wenwen Gao, Qianming Jiang, Juan J. Loor, Chenchen Zhao, Xiliang Du, Min Zhang, Yuxiang Song, Zhe Wang, Guowen Liu, Xinwei Li,Lin LeiTargeting IRE1α and PERK in the endoplasmic reticulum stress pathway attenuates fatty acid-induced insulin resistance in bovine hepatocytes,Journal of Dairy Science, 2022, 105(8): 6895-6908.

4.Lin Lei, Wenwen Gao, Juan J. Loor, Zhiyuan Fang, Xiliang Du, Min Zhang, Yuxiang Song, Guowen Liu,Xinwei LiReducing hepatic endoplasmic reticulum stress ameliorates the impairment in insulin signaling induced by high levels of β-hydroxybutyrate in bovine hepatocytes,Journal of Dairy Science, 2021, 104(12): 12845-12858.

5.Cai Zhang#, Qi Shao#, Mingchao Liu, Xueying Wang, Juan J Loor, Qianming Jiang, Shunan Cuan, Xinwei Li, Jianguo Wang, Yuanxiao Li, Lei He, Yong Huang, Guowen Liu*,Lin Lei*Liver fibrosis is a common pathological change in the liver of dairy cows with fatty liver.Journal of Dairy Science, 2023, 106(4): 2700-2715.

6.Jinxia Li#, Chenchen Zhao#, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Xinwei Li, Guowen Liu,Lin Lei*, Haihua Feng*Nuciferine ameliorates nonesterified fatty acid-induced bovine mammary epithelial cell lipid accumulation, apoptosis, and impaired migration via activating LKB1/AMPK signaling pathway.Journal of agricultural and food chemistry, 2022, 71(1): 443-456.

7.Chenchen Zhao#, Bing Wu#, Jinxia Li, Qianming Jiang, Juan J. Loor, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu,Lin Lei*, Xinwei Li*AdipoRon alleviates fatty acid–induced lipid accumulation and mitochondrial dysfunction in bovine hepatocytes by promoting autophagy.Journal of Dairy Science, 2023.

8.Chenchen Zhao, Jinxia Li, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu,Lin Lei*, Xinwei Li* Inhibition of cluster antigen 36 protects against fatty acids-induced lipid accumulation, oxidative stress, and inflammation in bovine hepatocytes.Journal of Dairy Science, 2023, 106(12): 9186-9199.

联系我们

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